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GeneGlobe ID: JHS-3002Z | Cat. No.: | QIAseq RNA Fusion XP Panels

RNA Fusion XP Pan Heme Panel

Kit containing ALL reagents (except indexes) for fusion and gene expression profiling by digital RNAseq

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Product Specification

Target List

Leukemia
Acute Leukemia of Ambiguous Lineage​
ABL1AFF1BCRCT45A2ETV6EWSR1GPHNKMT2AMLLT10MN1NUP214PBX1SETTCF3ZNF384
Acute Lymphoblastic Leukemia (ALL)​
ABL1ABL2 (ARG)ACTN4AFDNAFF1AFF3AFF4AGGF1ANLNASNSATF7IPAUTS2BCL11BBCL9BCRBTBD18CASC5CREBBP (CBP)CRLF2 (TSLPR)CSF1RDDX3XEBF1ELLELNEML1EP300EPOREPS15ESRRBETV6EWSR1FGFR1FGFR1OPFLT3FOXO4FOXP1FRYLGAS7GPHNHLFHNRNPUL1INPP5DJAK2KMT2AKMT2ELNP1MAML2MEF2DMLLT1MLLT10MLLT3MN1MNX1MYBMYCNCOA2NOTCH1NUP214NUP98P2RY8PAG1PAX5PBX1PCM1PDGFRBPICALMPMLPRDM16RAP1GDS1RARARCSD1RUNX1 (AML1)SALL2SETSFPQSPI1SSBP2STILSTMN1TAF15TAL1TCF3TCF7TET1TYK2USP9XZBTB16ZCCHC7ZMIZ1ZMYM2ZNF384ZNF521ATMBRAFCDKN2A (P16INK4A)CREBBP (CBP)CSF3R (GM-CSFR)DNM2EGFR (ERBB1)FBXW7GATA2HRASMAP2K1MLH1PAX5PDGFRAPTENSMARCB1
Acute Myeloid Leukemia (AML)​
ABI1ABI2ABL1AFDNAFF1AFF4ALKANLNARHGAP26ARHGEF12BCORBCRCASC5CBFA2T3CBFBCBLCCDC88CCEP170BCHD1CHIC2CREBBP (CBP)DAB2IPDDX10DEKDHHDIAPH2ELLEP300EPS15ERGETV6FGFR1FIP1L1FLNAFNBP1FOXO3FOXO4FRYLFUSGAS7GATA1GLIS2GPHNHAUS1HOXA9HOXC11HOXC13HOXD13IRF2BP2JAK2KAT6AKDM5AKIAA1524KMT2ALASP1LNP1LPPLYNMAML2MECOMMKL1MLF1MLLT1MLLT10MLLT11MLLT3MLLT6MN1MNX1MYBMYH11MYO1FNCKIPSDNCOA2NF1NPM1NSD1NTRK3NUMA1NUP214NUP98PAN3PBX1PCM1PDGFRAPDGFRBPDS5APHF23PICALMPMLPRDM16PRRX1PSIP1PSMA2PTPRRRANBP2RARARBM15RHEBL1RPL22RPN1RUNX1 (AML1)RUNX1T1SARNPSEPT2SEPT5SEPT6SEPT9SETSH3GL1SORBS2STAT5BTAF15TCF3TET1TFGTOP1TOP3ATRIP11TYK2UBA2USP42WHSC1L1WTIPZBTB16ZFYVE19ZNF384ASXL1ATMBCORBRAFCDKN2A (P16INK4A)CHEK2 (RAD53)CREBBP (CBP)CSF3R (GM-CSFR)DAXXDNM2FLT3GATA2IDH1IDH2JAK1JAK3KIT (CD117)KMT2DKRASMAP2K1MPLMYCNRASPBRM1PDGFRAPPM1DPTENPTPN11RAD21RETRUNX1 (AML1)SMARCB1SRSF2U2AF1WT1
Acute Myelomonocytic Leukemia (AMML)​
FLNAHOXD13NUP98
B-Cell Acute Lymphoblastic Leukemia (B-ALL)​
ABL1ACTN4AFF1AFF3AFF4ATF7IPBCRBTBD18CRLF2 (TSLPR)EPS15ERGESRRBETV6EWSR1FUSGAS7JAK2KMT2AMAPRE1MLLT1NUP214P2RY8PAX5PBX1PCM1RUNX1 (AML1)SETSSBP2TCF3USP9XZNF384ZNF521
Blast Phase Chronic Myeloid Leukemia​
ABL1BCRETV6JAK2
Chronic Eosinophilic Leukemia​
ACSL6TNIP1
Chronic Lymphocytic Leukemia (CLL)​
MYCNOTCH1BRAFCHEK2 (RAD53)CSF3R (GM-CSFR)MAP2K1TERT
Chronic Myeloid Leukemia (CML)​
ABL1BCRCCDC88CETV6HOXA11HOXA13JAK2MECOMMN1NDE1NUP98PCM1PDGFRBRUNX1 (AML1)ABL1CDKN2A (P16INK4A)CREBBP (CBP)CSF3R (GM-CSFR)FBXW7GATA2
Chronic Myelomonocytic Leukemia (CMML)​
CREBBP (CBP)ELLETV6KMT2AMN1CSF3R (GM-CSFR)HRASSRSF2
Myelodysplastic Syndromes (MDS)​
ABL1ACTN4ALKCASC5CREBBP (CBP)DEKERGETV6FRYLFUSHOXD13JAK2KMT2ALNP1MAML2MECOMMLF1MN1MNX1NDE1NPM1NUP214NUP98PCM1PDGFRBPRDM16PTPRRRANBP2RUNX1 (AML1)RUNX1T1TOP1CDKN2A (P16INK4A)CSF3R (GM-CSFR)ETNK1GNASHRASRAD21SETBP1SRSF2U2AF1XPO1ZRSR2
Myeloproliferative Neoplasms​
ABL1ACSL6BCRETV6FGFR1FGFR1OPFIP1L1FLT3HOXA9HOXD13JAK2LYNMECOMMLF1MN1NPM1NUP98PDGFRBPRKG2PSIP1RARARUNX1 (AML1)TNIP1ZMYM2ABL1ASXL1JAK2JAK3KRASMPLNRASSETBP1SF3B1SH2B3SRSF2
T-Cell Acute Lymphoblastic Leukemia (T-ALL)​
ABL1AFDNAGGF1ASNSBCL11BBCRCASC5DDX3XETV6JAK2KMT2AKMT2EMLLT1MLLT10NOTCH1NUP214PBX1RUNX1 (AML1)SALL2SETSPI1STILSTMN1TAL1TCF3TCF7
Other Leukemias​
BCL11BIKZF2IKZF3IRF2BP2MYCNPM1PDCD1LG2SETD2TYK2
Chronic Neutrophilic Leukemia (CNL)​
CSF3R (GM-CSFR)
Multiple Myeloma​
ATMBRAFCDKN2A (P16INK4A)EGFR (ERBB1)FBXW7HRASMYCPTENSMARCB1
Myeloid Malignancies​
CBLCBLBDNMT3AEZH2
Myelofibrosis​
CHEK2 (RAD53)IDH1IDH2SRSF2
Other Myeloid Neoplasms​
BRAFCDKN2A (P16INK4A)CUX1FBXW7HRASMYD88PTENSTAT3
Lymphoma
Acute Lymphoblastic Lymphomas​
BCL11BCREBBP (CBP)EBF1KMT2AMLLT10MYCP2RY8PRDM16STIL
Anaplastic Large Cell Lymphomas​
ADGRG7ALKATICCLTCMSNMYCNPM1TFGTPM3TPM4ALKCDKN2A (P16INK4A)DNMT3ANRASSTAT3
Angioimmunoblastic T Cell Lymphomas​
CD28CTLA4FIP1L1PDGFRAALKAPCARID1AASXL1ATMBRAFCDKN2A (P16INK4A)CREBBP (CBP)CTNNB1DNMT3AEZH2FBXW7IDH2JAK1JAK3KIT (CD117)KMT2DKRASMED12PLCG1RHOASTAT3WT1XPO1ZFHX3
Burkitt Lymphomas​
BCL6MYCPBX1TCF3APCARID1AATMCD79BCDKN2A (P16INK4A)CREBBP (CBP)FBXW7HLA-AID3KRASMYCMYD88NRASPAX5PIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)PTENRHOASRSF2
Diffuse Large B Cell Lymphomas (DLBCL)​
ALKBCL11ABCL6CCND3CIITACLTCIGLL5LPPMAPK13 (p38delta)MYCNPM1PIM1RELSQSTM1TBL1XR1TOMM40TP63ZCCHC7ALKAMER1APCARID1AASXL1ATMB2MBCL2BCORBRAFBTKCD79BCDKN2A (P16INK4A)CNOT3CREBBP (CBP)CTNNB1CXCR4DNMT3AEZH2FBXW7HLA-AID3IDH2IRS4JAK1JAK3KIT (CD117)KMT2DKRASMAP2K1MED12MSNMYCMYD88NCOR1NFKBIENOTCH2NRASNSD2PAX5PIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)PLCG1POT1PPM1DPTENRGS7RHOASF3B1SMOSRSF2STAT3STAT5BSTAT6TERTTRRAPWT1XPO1ZFHX3ZNF479
Follicular Lymphomas​
AFF3BCL2BCL6CIITAMYCTBL1XR1TP63AMER1ARID1AATMB2MBCL2BCORBRAFBTKCD79BCDKN2A (P16INK4A)CREBBP (CBP)CXCR4DNMT3AEZH2FBXW7ID3IDH2KMT2DMAP2K1MED12MYD88NOTCH2NRASPIK3R1 (p85-ALPHA)PPM1DPTENRGS7RHOASRSF2STAT6ZMYM3
Granulocytic Sarcomas​
RUNX1 (AML1)RUNX1T1
Hodgkin Lymphomas​
ALKCIITAJAK2NPM1SEC31AARID1AASXL1B2MBCORCDKN2A (P16INK4A)DNMT3AEZH2NFKBIENRASPAX5PIK3R1 (p85-ALPHA)PPM1DSF3B1
Inflammatory Myofibroblastic Tumors​
ALKDCTN1
Lymphoblastic Lymphomas​
BCRCRLF2 (TSLPR)EPORETV6FGFR1NOTCH1PBX1PDGFRBRARAZCCHC7
Lymphoblastic T Cell Lymphomas​
BCRETV6FGFR1FIP1L1LYNPDGFRA
Mantle Cell Lymphomas​
CCND3MYCARID1AASXL1ATMB2MBCORBRAFBTKCDKN2A (P16INK4A)CREBBP (CBP)DNMT3AIDH2KMT2DKRASMED12NCOR1NFKBIENOTCH2NRASNSD2PAX5POT1PPM1DPTENSTAT3TERTZFHX3
Mediastinal Large B Cell Lymphomas (MLBL)​
CIITAPDCD1LG2
Mucosa-Associated Lymphoid Tissue (MALT) Lymphomas​
BCL6BIRC3 (c-IAP2)CCND3MALT1MYCMYD88NOTCH2
Peripheral T Cell Lymphomas​
ALKETV6FGFR3IKZF2ITKMYO1FNPM1S100A7SYKTBL1XR1THAP4TP63VAV1ALKARID1AASXL1ATMCDKN2A (P16INK4A)CTNNB1DNMT3AIDH2IRS4KIT (CD117)KMT2DKRASMAP2K1MSNNRASPLCG1PTENRGS7RHOASTAT3STAT5BTRRAPXPO1ZFHX3ZNF479
Precursor T Cell Lymphoblastic Lymphomas​
ABL1JAK2NUP214PCM1SETCTNNB1FBXW7NRASWT1
T Cell Lymphomas​
ATXN2LBCL11BFGFR1IKZF2JAK2
Other Lymphomas​
BCL6BIRC3 (c-IAP2)CBFBCCND1CCND3CDK6CHIC2DEKDUSP22EIF4A1KMT2AMALT1MKL1MLF1MLLT10MYCNFKB2PICALMPRDM16
AIDS-Related Lymphomas​
EZH2
B Cell Lymphomas​
ARID1AATMB2MBCL2BCORBRAFCD79BCDKN2A (P16INK4A)CREBBP (CBP)CTNNB1CXCR4DNMT3AEZH2JAK3KIT (CD117)KMT2DMAP2K1MYD88PIK3CA (p110-alpha)PPM1DPTENRHOASTAT3
Small Lymphocytic Lymphomas​
ALKAPCARID1AASXL1ATMBCL2BCORBRAFBTKCD79BCDKN2A (P16INK4A)CNOT3CREBBP (CBP)CXCR4DNMT3AFBXW7GNASIRS4JAK1JAK3KIT (CD117)KMT2DKRASMAP2K1MED12MSNMYCMYD88NCOR1NFKBIENOTCH2NRASPAX5PIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)PLCG1POT1PPM1DPTENRGS7SF3B1STAT5BSTAT6TERTTRRAPXPO1ZFHX3ZMYM3ZNF479
Cutaneous T Cell Lymphomas​
KRASPTEN
Diffuse Red Pulp Small B Cell Lymphomas​
MYD88NOTCH2
Enteropathy-Type T Cell Lymphomas​
STAT5B
Gamma-Delta T Cell Lymphomas​
STAT3STAT5B
Hepatosplenic T Cell Lymphomas​
STAT3STAT5B
Lymphoplasmacytic Lymphomas​
ARID1ABTKCD79BCXCR4DNMT3AMYD88
Marginal Zone Lymphomas​
AMER1ARID1AASXL1ATMBRAFCD79BCREBBP (CBP)CXCR4DNMT3AEZH2FBXW7GNASJAK3KIT (CD117)KMT2DMAP2K1MYD88NFKBIENOTCH2PIK3R1 (p85-ALPHA)RHOASRSF2TRRAPXPO1
Mycosis Fungoides (Sezary Syndrome)​
AMER1ARID1AATMBCORCDKN2A (P16INK4A)DNMT3AJAK1JAK3KMT2DKRASNCOR1NRASPIK3CA (p110-alpha)PLCG1POT1PTENSTAT3STAT5B
NK-T Cell Lymphomas​
ALKAMER1APCARID1AASXL1ATMB2MBCORBRAFCTNNB1DNMT3AEZH2FBXW7HLA-AJAK1JAK3KIT (CD117)KMT2DKRASMED12NCOR1NOTCH2NRASPOT1RGS7RHOASMOSTAT3STAT5BWT1XPO1ZFHX3
Primary Central Nervous System Lymphomas​
B2MBCL2CD79BCDKN2A (P16INK4A)CXCR4DNMT3AHLA-AJAK3KIT (CD117)KRASMYD88NOTCH2POT1STAT3STAT5BTERTTRRAPWT1
Primary Effusion Lymphomas​
CDKN2A (P16INK4A)PTEN
Myelodysplastic Syndromes (MDS)
ABL1ACTN4ALKCASC5CREBBP (CBP)DEKDIAPH2ERGETV6FGFR1FRYLFUSGOT1HOXA11HOXA13HOXD13JAK2KMT2ALNP1MAML2MECOMMLF1MN1MNX1MYH11NDE1NPM1NUP214NUP98PAN3PCM1PDGFRBPRDM16PSMA2PTPRRRANBP2RUNX1 (AML1)RUNX1T1SEPT9SYKTOP1ZMYM2
Myeloproliferative Neoplasms
ABL1ACSL6BCRCNTRLETV6FGFR1FGFR1OPFIP1L1FLT3FOXP1HOXA9HOXD13JAK2KANK1LYNMECOMMLF1MN1NPM1NUP98PCM1PDGFRAPDGFRBPRKG2PSIP1RARARUNX1 (AML1)TNIP1
Other Hematological Malignancies
Eosinophilia​
ETV6FOXP1LYNPDGFRA
Langerhans Cell Histiocytosis​
NTRK3PLEKHA6
Plasma Cell Myelomas​
ABL1BCR
Polycythemia Vera​
GTF2H3
Severe Thrombocythemia​
KANK1PDGFRB
Other Myeloid Neoplasms
KLF2PTK2B (PYK2)SEMA6A
Commercial Control Samples
ALKBAIAP2L1BRAFCCDC6CD74EGFR (ERBB1)EML4ERGETV6FGFR3KIF5BLMNAMETNCOA4NTRK1NTRK3PAX8PPARGRETROS1SEPT14SLC34A2SLC45A3TACC3TFGTMPRSS2TPM3
General Leukemia Markers
ANPEPCD19CD200CD33CD34CD38CR2FOXM1FOXO3HOXA9ITGA6KIT (CD117)MS4A1RUNX1 (AML1)
Leukemia Subtype Markers
Acute Lymphoblastic Leukemia (ALL)​
ANPEPBTG1CASP8AP2CD19CD1ACD2CD22CD33CD5CD7CD79ACD8ACR2ETV6HLA-DRAHLA-DRB1IL2RA (CD25)JUNKIT (CD117)LMO1LMO2LYL1MEIS1MMEMS4A1MYCPBX1PTPRCRB1VEGFAWT1
B Cell Acute Lymphoblastic Leukemia (B-ALL)​
BTG1CD300ACD72CD79ACD79BCD86CDKN2A (P16INK4A)CDKN2B (p15INK4b)CRLF2 (TSLPR)EBF1ETV6HOXA9IKZF1PAX5RB1
T Cell Acute Lymphoblastic Leukemia (T-ALL)​
BTKCD27 (TNFRSF7)CD4KCNN4LMO1LMO2LYL1MMP9RUNX1 (AML1)SERPINI1TAL1THBS1 (TSP-1)TLX1TLX3VPREB3
Acute Myeloid Leukemia (AML)​
ADGRE5 (CD97)ASS1BAALCBCL11BBIRC5CD200CD300ACD44CD86CD96CD99CLEC12AERGFCGR2AFLT3HAVCR2IL2RA (CD25)JUNKIT (CD117)KLF4LEF1MECOMMEIS1MMP9NPM1PTPRCTHBS1 (TSP-1)VEGFAWT1
Chronic Lymphocytic Leukemia (CLL)​
ABCA6AIM2AKT1BAXBCL2BIRC2 (c-IAP1)BTKCD19CD200CD24CD27 (TNFRSF7)CD5CD79BCXCR4IL7ITGA4 (CD49D)ITGAMJUNKCNN4LAIR1LEF1MCL1MMP9MS4A1ROR1SERPINI1SOX11THBS1 (TSP-1)TNFTTNVEGFAVPREB3WNT3
Chronic Myeloid Leukemia (CML)​
AURKAAURKBIL2RA (CD25)JUNKIT (CD117)PTCH1PTPRC
Other Leukemia Subtypes​
CD72IL2RA (CD25)SPI1
Leukemia Stem Cell & Proliferation Markers
ADGRG1BAALCBMI1CD33CD34CD44CD47CD96CD99CLEC12ACXCL12 (SDF1)CXCR4ERGFCGR2AHAVCR2IL2RA (CD25)IL3RAKIT (CD117)KLF4LAIR1LIN28AMYCPOU5F1 (OCT4)PTPRCSOX2THY1WT1
Possible Prognostic Significance
Indicator of Clinical Outcome in Leukemia​
AURKBBAALCBIRC5ERGFOXO3GATA2MECOMMEIS1RUNX1 (AML1)SPI1WT1
Acute Lymphoblastic Leukemia (ALL)​
ABCB1 (MDR1, PGY1)AKT1ANPEPBIRC5CD33CD3DCD44FLT3HOXA9IKZF1JUNMMEMYCPAX5SMYD2
B Cell Acute Lymphoblastic Leukemia (B-ALL)​
ANPEPCD33CRLF2 (TSLPR)JUNMS4A1
T Cell Acute Lymphoblastic Leukemia (T-ALL)​
BCL11BBMI1LMO1LMO2LYL1MYCTAL1TLX1TLX3
Acute Myeloid Leukemia (AML)​
ABCB1 (MDR1, PGY1)ANGPT2BAALCBCL2BIRC2 (c-IAP1)BIRC5BMI1CCNA1CD200CD34CD4CD44CD47CD96CLEC12ACXCL12 (SDF1)CXCR4ERGGATA2HAVCR2HGFIL2RA (CD25)IL3RAKLF4LEF1MECOMMEIS1MN1MYCRUNX1 (AML1)SOX11SOX2SPI1WT1XIAP
Chronic Lymphocytic Leukemia (CLL)​
ABCA6ANGPT2BCL2CD24CD38CD69ITGA4 (CD49D)KCNN4LAIR1LPLMS4A1MYCNOTCH1ROR1SOX11TTNUGT2B17VPREB3WNT3ZAP70
Chronic Myeloid Leukemia (CML)​
AURKAAURKBLIN28AMCL1PTCH1
Chemotherapy Resistance Related​
AKT1AURKBBAALCBCL2BIRC2 (c-IAP1)CD274 (PD-L1)CD274 (PD-L1)CD44CD47ERGHLA-DRAHLA-DRB1IL3RAMCL1MYCXIAP
Hypoxia & Oxidative Stress Related​
ANGPT2VEGFA
Treatment Target or Treatment Indicator​
ASS1BMI1CASP8AP2CD33CD47CD69CD96CDC25ACDKN2A (P16INK4A)CDKN2B (p15INK4b)CLEC12ACXCR4FLT3FOXM1FOXO3HAVCR2IL3RAITGAMKLF4LMO2MS4A1MYCPTCH1SERPINI1SMARCA4TAL1ZAP70
Associated with Invasiveness or Infiltration into Central Nervous System​
CXCL12 (SDF1)CXCR4ZAP70
Minimal Residual Disease​
ADGRE5 (CD97)BAALCBCL2CD19CD200CD24CD300ACD44CD47CD69CD72CD79BCD86CD99CLEC12AHAVCR2IL2RA (CD25)IL3RAITGA6NPM1PBX1WT1
Mechanistic Role in Pathogenesis
BCL11BBCL2BMI1ERGFOXM1GATA2HOXA9LMO2LPLMEIS1NOTCH1PAX5SPI1TAL1TLX1TLX3TNFVEGFAWT1
Expression Altered due to Genetic Alterations
Acute Lymphoblastic Leukemia (ALL)​
AHI1BCL11ABCL2BCL9BRD4CCND2CEBPACEBPBCEBPDCEBPECEBPGCRLF2 (TSLPR)EPORETV6HOXA1ID4IGF2BP1IL3IRF4IRS4LCKLHX4LMO1LMO2LYL1MYBMYCNKX2-5NOTCH1OLIG2TAL2TLX1TLX3
Acute Myeloid Leukemia (AML)​
MECOMNKX2-5RANBP17TCL1ATLX3
Lymphoma​
BCL10BCL2BCL3BCL6BCL9CCND1CCND2CCND3CD44CDK6ERVW-1FCGR2BFCRL4FOXP1GPR34IRF4KDSRMALT1MTCP1MUC1 (mucin)MYCNBEAP1NFKB2PAX5PRDM16
Myelomas​
FGFR3MAFMAFBNSD2
Other Leukemia Subtypes & Other Genetic Alterations​
BAALCBCL11BCRLF2 (TSLPR)ERGKIT (CD117)LMO1LPLNPM1TAL1ZAP70

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Introducing the RNA Fusion XP Pan Heme Panel, a cutting-edge addition to our QIAseq RNA Fusion XP Panels lineup, specifically designed for {{application}} applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the RNA Fusion XP Pan Heme Panel facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting {{application}}, or any other sophisticated analyses, this product from our QIAseq RNA Fusion XP Panels collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with RNA Fusion XP Pan Heme Panel and elevate your work to new heights.
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