Target List
Skeletal Muscle Contractility
Dystrophin-Glycoprotein Complex
CAMK2GCAPN3CAV3DAG1DMDDYSFLMNAMAPK1 (ERK2)SGCA
Titin Complex
ACTA1ACTN3CAPN3CRYABDESLMNAMAPK1 (ERK2)MSTNMYH1MYH2MYOTNEBSGCATNNI2TNNT1TNNT3TRIM63 (MURF1)TTN
Energy Metabolism
CSHK2PDK4SLC2A4 (GLUT4)
Fast-Twitch Fibers
ATP2A1MYH1MYH2TNNI2TNNT3
Slow-Twitch Fibers
MBMYH1TNNC1TNNT1
Other Skeletal Muscle Contractility Genes
DMPKIKBKB (IKKβ)RPS6KB1
Skeletal Myogenesis
ACTA1ADRB2AGRNBCL2BMP4CAPN2CASTCAV1CTNNB1DMDHDAC5IGF1IGFBP3IGFBP5MEF2CMSTNMUSKMYF5MYF6MYOD1MYOGPAX3PAX7PPP3CARHOARPS6KB1UTRN
Skeletal Muscle Hypertrophy
ACTA1ACVR2BADRB2IGF1IGFBP5MSTNMYF6MYOD1RPS6KB1
Skeletal Muscle Autocrine Signaling
ADIPOQ (ACRP30)FGF2 (BFGF)IGF1IGF2IL6LEP (Leptin)MSTNTGFB1
Diabetes / Metabolic Syndrome
ADIPOQ (ACRP30)LEP (Leptin)PPARGPPARGC1A (PGC-1α)PPARGC1B (PGC-1β)PRKAA1 (AMPK)PRKAB2PRKAG1PRKAG3SLC2A4 (GLUT4)
Skeletal Muscle Wasting / Atrophy
Autophagy
CAPN2CASP3FBXO32FOXO1FOXO3MSTNNOS2 (iNOS)PPARGC1A (PGC-1α)PPARGC1B (PGC-1β)RPS6KB1TRIM63 (MURF1)
Dystrophy
AKT1AKT2FBXO32IL1BMAPK1 (ERK2)MAPK14 (p38ALPHA)MAPK3 (ERK1)MAPK8 (JNK1)MMP9NFKB1TNFTRIM63 (MURF1)UTRN