Target List
PPARα Targets
Adipogenesis
ADIPOQ (ACRP30)LPLNR1H3UCP1
Fatty Acid Metabolism
ACADLACADMACOX1ACOX3ACSL1ACSL3ACSL4ACSL5CPT1ACPT1BCPT2CYP27A1CYP4A11CYP7A1EHHADHFADS2HMGCS2PLTPSCD
Lipid Transport
ADIPOQ (ACRP30)ANGPTL4APOA1APOA5APOC3LPLNR1H3OLR1
Insulin Signaling
CPT1ASORBS1
PPARβ & PPAR[delta] Targets
Adipogenesis
ADIPOQ (ACRP30)ECH1FABP4LPLUCP1
Fatty Acid Metabolism
ACAA2ACADLACADMACOX1ACOX3ACSL1ACSL3ACSL4ACSL5CPT1ACPT1BCPT2CYP4A11CYP27A1CYP7A1EHHADHETFDHFABP1FABP3FABP4FADS2GKHMGCS2MLYCDPLTPSCDSLC27A1SLC27A4
Lipid Transport
ADIPOQ (ACRP30)ANGPTL4LPLOLR1
Cell Proliferation
HIF1AILKKLF10PTEN
Insulin Signaling
CPT1APDPK1SORBS1
Other PPARβ & PPAR[delta] Target Genes
PDPK1
PPARγ Targets
Adipogenesis
ADIPOQ (ACRP30)LPLNR1H3UCP1
Fatty Acid Metabolism
ACADLACADMACOX1ACOX3ACSL1ACSL3ACSL4ACSL5CPT1ACPT1BCPT2CYP27A1CYP4A11CYP7A1EHHADHFADS2GKSCD
Lipid Transport
ADIPOQ (ACRP30)ANGPTL4APOEDGAT1LPLNR1H3OLR1
Cell Proliferation
CLUELNTXNIP
Insulin Signaling
CPT1ADGAT1PCK1SORBS1
Other PPARγ Target Genes
MMP9PCK1PCK2
PPAR Cofactors
CHD9CREB1CREBBP (CBP)EP300FGRLPIN1MED1NCOA3NCOA6PPARGC1A (PGC-1α)PPARGC1B (PGC-1β)PPRC1HELZ2SIRT1SMARCD3SRCTGS1
PPAR Ligand Transport
CD36FABP1FABP2FABP3FABP4FABP5FABP6FABP7SLC22A5SLC27A1SLC27A2SLC27A4SLC27A5SLC27A6
PPAR Transcription Factors
PPARAPPARDPPARGRXRARXRBRXRG