Target List
Acute Rejection - Innate Immunity
Pattern Recognition Receptors (PPRs)
Tlr3Tlr4Tlr9
Cytokines
Ccl11 (Eotaxin)Ccl2 (Mcp-1)Ccl4 (Mip-1b)Ccl5 (Rantes)Csf2 (Gm-csf)Csf2 (Gm-csf)Csf2 (Gm-csf)Ctla4Cxcl10 (Inp10)IfngIl10Il12aIl12bIl13Il16Il1bIl2Il2ra (Cd25)Il3Il4Il5Il6LOC103694380 (Tnf)
Other Innate Immunity Genes
Adam17 (Cd156b)C3C4aCasp1 (Ice)Casp3Casp8 (Flice)Ccr3Cd14Cd28Cd8aFasFaslgGzmaGzmbMs4a1Nfkb1Nos2 (Nos2a, iNos)Prf1Psmb9Stat1Stat6Tap1 (Abcb2)Tnfaip3Tnfsf10 (Trail)
Acute Rejection - Adaptive Immunity
Th1 Markers & Immune Response
Ccr5Ccr7Cd80Cxcr2Cxcr3Ifng
Th2 Markers & Immune Response
Cd86Il10Il13Il4Il5Il6
T-Cell Activation
Cd80Cd86Icam1Ifng
Cytokines
Ccl2 (Mcp-1)Ccl4 (Mip-1b)Ccl5 (Rantes)Csf2 (Gm-csf)Csf2 (Gm-csf)Csf2 (Gm-csf)Cxcl10 (Inp10)IfngIl10Il13Il4Il5Il6LOC103694380 (Tnf)
Leukocyte Recruitment
Cd40Cd40lgIcam1Thbs1 (TSP-1, Tsp1)Vcam1
Chronic Rejection
Pro-Fibrotic
Ccl3 (Mip-1a)Ccn2Il13Il4Il5
Anti-Fibrotic
Bmp7Col1a2IfngIl10Thbs2
Cell Adhesion Molecules
Icam1Itga2ItgadItgaeVcam1
Cellular Infiltration
Bmp7Cd44Col1a2Cx3cr1Cxcl11 (I-Tac, Ip-9)Cxcl9Cxcr4Mmp1Mmp1bMmp2Mmp7Mmp9Tgfb1Tgfb2Tgfb3Thbs2Timp1Vegfa
Other Transplant Rejection Genes
OsmSmad3