GeneGlobe ID: PAHS-3012Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human Apoptosis 384HT

RT2 Profiler PCR Array

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Product Specification

Target List

Caspases & Regulators
Caspases​
CARD17CARD18CASP1 (ICE)CASP10 (MCH4)CASP14CASP2CASP3CASP4CASP5CASP6CASP7CASP8 (FLICE)CASP9CFLAR (CASPER)CRADDMALT1PYCARD (TMS1, ASC)COP1
Caspase Activation​
AIFM3APAF1BAXBBC3 (PUMA)BCL2L10BCL2L13CASP1 (ICE)CASP8AP2CASP9COL4A3CYCSDIABLOEIF2AK3F2 (Thrombin)F2R (PAR1)FOXL2HIP1HSPE1IFNB1IFT57LCKMAP3K5MOAP1MTCH1MYCNLRC4 (IPAF)NLRP1NLRP12NLRP2NLRP3NOD1 (CARD4)PMAIP1 (NOXA)PYCARD (TMS1, ASC)STAT1TNFRSF10A (TRAIL-R)TNFRSF10B (DR5)TNFSF15TP53 (p53)TPD52L1VCP
Caspase Inhibition​
BIRC5CD27 (TNFRSF7)DHCR24IFI6LAMTOR5SFN (14-3-3σ, YWHAS)TNFAIP8TNFSF14TRIAP1XIAP
Anti-Apoptotic
Positive Regulation of Anti-Apoptosis​
BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BRECD28ERC1MAPK8IP2 (JIP-1)OPA1PRKAA1 (AMPK)RASA1
Negative Regulation of Anti-Apoptosis​
PIK3R2 (p85-BETA)RTN4TNFAIP8
Other Anti-Apoptotic Genes​
AATFAKT1ALOX12ANXA1ANXA4API5ATF5AVENAZU1BAG1BAG3BAG4BCL2BCL2A1 (BFL1)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L10BCL2L2BDNFBECN1BFARBIRC2 (c-IAP1)BIRC3 (c-IAP2)BIRC5BIRC6BIRC7BIRC8BNIP1BNIP2BNIP3BRAFCASP2CBX4CCL2 (MCP-1)CD27 (TNFRSF7)CD40LGCEBPBCFDP1CFL1CFLAR (CASPER)CRYAACRYABDAD1DDAH2DHCR24EEF1A2FAIMFAIM2FASFOXO1GDNFGFRALGLO1GSTP1HDAC1HDAC3HIPK3HMGB1HSP90B1HSPA1BHSPA9HSPB1 (HSP27)HTATIP2HTTIER3IFI6IGF1RIL10IL1AIL2IL31RALAMTOR5MALT1MCL1MKL1MPOTESMINMYBL2MYO18ANAIPNFKB1NME5NOL3NOTCH2NPM1NRG2NTF3PAK7PAX7PEA15PIK3CA (p110-alpha)PIM2POGKPOLBPRDX2PRKCZPRLRPROK2PSEN1RELARNF7SEMA4DSERPINB2 (PAI-2)SERPINB9SFRP1SH3GLB1SNCASOCS2SOCS3SONSPHK1SPP1STAMBPTAX1BP1TBX3TGFB1TIAF1TMX1TNFTNFAIP3TNFAIP8TNFRSF10DTNFRSF18TNFRSF6BTNFSF18TPT1TRIAP1TSC22D3VEGFAVHLXIAPYWHAZZC3HC1
Induction of Apoptosis
Induction of Apoptosis by Death Domain Receptors​
BIDCRADDDAXXDEDD2FADDIL18TNFTNFRSF10B (DR5)
Induction of Apoptosis by DNA Damage​
ABL1AIFM1BCL3BRCA1CHEK2 (RAD53)CIDEACIDEBDYRK2IFI16MBD4MSH6PCBP4PMLSFN (14-3-3σ, YWHAS)TP53 (p53)TP73
Induction of Apoptosis by Oxidative Stress​
GPX1PRODHRNF7TP53I3 (PIG3)
Induction of Apoptosis by Extracellular Signals​
ADORA1BTKCASP8AP2CD28CD38CD5CFLAR (CASPER)DAPDAP3DAPK1DPF2FASTKMAP3K5NDUFA13PDCD6PRKCARIPK3SPNTIMP3TNFRSF25 (DR3)
Induction of Apoptosis by Intracellular Signals​
CDKN1A (p21CIP1, WAF1)CUL1CUL2CUL3CUL4ACUL5HIPK2MYCSART1
Other Pro-Apoptotic Genes​
ACVR1BAIFM2AIFM3ALOX15BAPOEBADBAK1BAXBBC3 (PUMA)BCL10BCL2L11BCL2L13BCLAF1BIKBNIP1BNIP3BNIP3LBOKCASP10 (MCH4)CASP3CASP4CASP6CD2CD27 (TNFRSF7)CD70CEBPBCIDECCOL4A3DAPK2DAPK3DCCDDX20DEDDDIABLOEI24ERCC2 (XPD)ERCC3 (XPB)ERN1ERN2FASFASLG (TNFSF6)FEM1BFOXL2FOXO3HRKHTATIP2IFNA2IFNB1IFNGIKBIPIKBKGIL19INHAINHBAJMYLALBALCKLTA (TNFB)MALMAP3K10MAPK1 (ERK2)MX1NDUFS3NGFRNLRP1NLRP3NME3NOTCH2NOX5NUDT2NUPR1PDCD5PLAGL1PLAGL2PLEKHF1PLGPMAIP1 (NOXA)PPP1R13BPPP2CAPPP2R1APPP2R1BPRKCEPRKRAPRUNE2PTENPTHPYCARD (TMS1, ASC)RPS3ARUNX3S100BSAP30BPSERINC3SIPA1SMNDC1SSTSSTR3STK17ASTK17BTBX5TIA1TIAL1TLR2TNFRSF10A (TRAIL-R)TNFRSF19TNFRSF9TNFSF10 (TRAIL)TNFSF14TNFSF8TP53BP2TP63TPD52L1TRADDTRAF3TRAIPUNC13BUTP11LZNF443
TNF Domain Proteins
EDAFASLG (TNFSF6)LTA (TNFB)LTBTNFTNFSF10 (TRAIL)TNFSF14TNFSF15TNFSF8
TNFR Domain Proteins
CD27 (TNFRSF7)CD40 (TNFRSF5)FASLTBRNGFRTNFRSF10A (TRAIL-R)TNFRSF10B (DR5)TNFRSF10DTNFRSF18TNFRSF19TNFRSF1A (TNFR1)TNFRSF1BTNFRSF21TNFRSF25 (DR3)TNFRSF6BTNFRSF8TNFRSF9
BCL2 & BAG Domain Proteins
BAG1BAG3BAG4BAXBCL2BCL2A1 (BFL1)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L10BCL2L13BCL2L2MCL1
BIR Domain Proteins
BIRC2 (c-IAP1)BIRC3 (c-IAP2)BIRC5BIRC6BIRC7BIRC8NAIPXIAP
CARD Domain Proteins
APAF1BCL10BIRC2 (c-IAP1)BIRC3 (c-IAP2)CARD10CARD11CARD14CARD17CARD18CARD6CARD9CASP1 (ICE)CASP2CASP4CASP5CASP9CRADDNLRP1NOD1 (CARD4)NOD2NOL3PYCARD (TMS1, ASC)COP1RIPK2
Death Domain Receptors
CRADDDAPK1EDARFADDMALT1NFKB1NFKB2NGFRPIDD1 (PIDD)RIPK1TNFRSF10A (TRAIL-R)TNFRSF10B (DR5)TNFRSF1A (TNFR1)TNFRSF21TNFRSF25 (DR3)TRADD
TRAF Domain Proteins
TRAF2TRAF3TRAF5TRAF7
Other Apoptosis Regulators
BCL6CEBPGDBPDDIT3 (GADD153, CHOP)GRM4LGALS1MADDMAPK8 (JNK1)NKX3-2POU4F1PROP1RARGSTAT5ASTAT5BTBK1TDGF1TRAF6MAP3K20

Product Resources

Gene Table for 384-well Array
File Size: 181.78 KBLanguage: English

Resources

Brochures & Guides (3)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Safety Data Sheets (1)
Download Safety Data Sheets for QIAGEN product components.
Download Files (3)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Poster for download
Kit Handbooks (1)
For pathway-focused gene expression profiling using real-time RT-PCR
Instrument Technical Documents (2)
For gene expression and genomic analysis
For pathway-focused gene expression analysis
Certificates of Analysis (1)
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