Target List
Necrosis
Regulation of Necrosis
FasFaslRipk1Slc25a4Tnf
TNF-Induced Necrosis
9430015G10RikAtp6v1g2BmfCcdc103Commd4CyldDefb1Dennd4aDpysl4Eif5bFoxi1Galnt5Grb2Hspbap1Jph3Kcnip1MagOlfr1404Parp2PvrRab25S100a7aSpata2Sycp2Maco1Txnl4b
Other Necrosis Genes
Cd40FaddMgea5Ripk1Ripk3Parp1PpiaTmem123
Potential Necrosis Genes
RIPK1 Interactors
FusNfkb1Ripk2Ripk3
RIPK3 Interactors
Glud1GlulPyglRipk1
PARP1 Interactors
Capn1Capn2Capn3Capn5Capn6Capn7Capns1Ppid
Death Domain Receptors
FasTnfrsf1a (Tnfr1)Tnfrsf10b (Dr5)
Death Receptor Signaling
BidBirc3 (cIAP1, cIAP2)Casp8ap2CyldEda2rFaddFaf1Fem1bIkbkgPidd1MaddMyd88NgfNgfrBex3Parp1Ripk1Tnfrsf14Tnfrsf17Tnfrsf1bTnfrsf25 (Dr3)Tnfrsf4 (Ox40)Tnfrsf8Tnfsf15TraddTraf2
Apoptosis
Pro-Apoptotic
Aifm1BaxBidBmfBnip3lCasp8ap2FaddFaf1FasFaslFem1bIkbkgPidd1MaddNgfrBex3Ripk1Ripk2Ripk3TnfTnfrsf10b (Dr5)Tnfrsf25 (Dr3)Tnfrsf8Tnfsf10 (Trail)TraddTraf2
Anti-Apoptotic
Birc3 (cIAP1, cIAP2)Bnip3lFasMyd88Nfkb1NgfNgfrRipk1Ripk2TnfTnfrsf1a (Tnfr1)Tnfrsf1bTnfrsf4 (Ox40)Traf2
TNF-Induced Apoptosis
Atp6v1g2CyldSpata2Sycp2
Oxidative Stress
Aifm1CybaCybbGlud1Nox1Nox4
Mitochondrial Genes
Aifm1BaxBidBnip3lCybaCybbGlud1GlulPpidRipk1Slc25a4