Arthritis

Arthritis describes over 100 diseases involving joint inflammation (1, 2). JAK/STAT signaling, NF-κB signaling, Wnt signaling, p38 MAPK signaling, and PI3K/AKT signaling are a few of the pathways implicated in the pathogenesis of rheumatoid arthritis and osteoarthritis, the two most common types of arthritis.