Target List
Up-Regulated During Epithelial-to-Mesenchymal Transition
AhnakCald1Camk2n1Cdh2Col1a2Col3a1Col5a2Fn1Foxc2Gng11GscIgfbp4Itga5ItgavMmp2Mmp3Mmp9MsnSerpine1Snai1Snai2Snai3Sox10SparcSteap1Tcf4Timp1Tmeff1Tmem132aTwist1VcanVimVps13aWnt5aWnt5b
Down-Regulated During Epithelial-to-Mesenchymal Transition
Cav2Cdh1DspFgfbp1Il1rnKrt19MitfOclnRgs2Spp1Tfpi2Tspan13
Differentiation & Development
Akt1Bmp7Col3a1Col5a2Ctnnb1DspErbb3F11rFgfr2Foxc2Fzd7GscJag1Krt14Map1bMitfNodalNotch1Ppp3r1Ptp4a1Smad2Snai1Snai2Sox10Tgfb2Tgfb3Tmeff1Twist1VcanWnt11Wnt5aWnt5b
Cell Morphogenesis
Ctnnb1Foxc2Jag1Rac1Smad2Snai1Sox10Tgfb1Tgfb2Tgfb3Twist1Wnt11Wnt5a
Cell Growth & Proliferation
Akt1Bmp7Cav2Ctnnb1EgfrErbb3Fgfbp1Foxc2Igfbp4IlkJag1NodalPdgfrbTgfb1Tgfb2Tgfb3Timp1VcanZeb1
Cell Migration & Motility
Cald1Cav2EgfrFn1Itgb1Jag1MsnNodalPdgfrbRac1Stat3Tgfb1Vim
Cytoskeleton Regulators
Cav2Krt7Plek2Rac1Vim
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Bmp7Ccn2Cdh1Cdh2Col1a2Col3a1Col5a2Ctnnb1Dsc2EgfrErbb3F11rFgfr2Fn1Foxc2IlkItga5ItgavItgb1Mmp2Mmp3Mmp9Ptk2Rac1Serpine1Spp1Tgfb1Tgfb2Timp1Vcan
Signal Transduction
Estrogen Receptor Signaling
Cav2Esr1Krt19Tgfb3
G-Protein Coupled Receptor Signaling
Akt1Fzd7Gng11Rac1Rgs2
Integrin-Mediated Signaling
Ccn2Col3a1IlkItga5ItgavItgb1Ptk2
Notch Signaling
Foxc2Jag1Notch1
Receptor Tyrosine Kinase Signaling
EgfrErbb3Fgfr2PdgfrbRgs2Sparc
TGFβ / BMP Signaling
Bmp7Col3a1Fkbp1aSmad2Tgfb1Tgfb2Tgfb3
WNT Signaling
Ctnnb1Fzd7Gsk3bWnt11Wnt5aWnt5b
Transcription Factors
Ctnnb1Esr1Foxc2Gemin2GscMitfNotch1Smad2Snai2Snai3Sox10Stat3Tcf4Tcf7l1Twist1Zeb1Zeb2