Target List
TGFβ Superfamily Ligands
Activins
InhaInhbaInhbb
Bone Morphogenetic Proteins
AmhBmp1Bmp2Bmp3Bmp4Bmp5Bmp6Bmp7Gdf3Gdf5Gdf6Gdf7
Nodal
Nodal
TGFβ Family Members
Tgfb1Tgfb2Tgfb3
Inhibitors & Cofactors of TGFβ Signaling
BambiChrdDcnFstLtbp1Ltbp2NogTdgf1TgfbiTgfbrap1Tgif1Thbs1
TGFβ Superfamily Receptors
Activin Receptors
Acvr1Acvr2aAcvrl1
Bone Morphogenetic Protein Receptors
Amhr2Bmpr1aBmpr1bBmpr2
TGFβ Receptors
Tgfbr1Tgfbr2Tgfbr3
Transcription Factors & Regulators
Dlx2FosGscHipk2Id1JunJunbMycRunx1Smad1Smad2Smad3Smad4Smad5Smad6Smad7Sox4Stat1Tgfb1i1Tsc22d1
SMAD Target Genes
TGFβ / Activin-Responsive
Atf4Cdkn1aCdkn1bCdkn2bCol1a1Col1a2DcnEmp1FosGadd45bGscHerpud1Ifrd1Igf1Igfbp3Il6JunJunbMycPdgfbPlatSerpine1Tgfb1i1TgfbiTgif1Tnfsf10Tsc22d1
Bone Morphogenetic Protein Responsive
BglapDlx2Id1Id2JunbSox4Stat1
Molecules Regulating TGFβ Superfamily Signaling
BambiBmperCdkn2bChrdEngFstHipk2MecomNogPlauRunx1
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Cell Adhesion Molecules
BglapEngTgfb1i1Tgfbi
Extracellular Matrix (ECM) Structural Constituents
BglapCol1a1Col1a2Ltbp1Ltbp2PlatTgfbi
Cellular & Developmental Processes
Apoptosis
Cdkn1aCdkn1bIgfbp3InhaInhbaStat1Tgfb1
Embryonic Development
Bmp4InhbaMecomSmad3Tdgf1
Muscle Development
DcnIgf1Smad3
Neurogenesis
Dlx2InhaInhbaNog
Reproduction
AmhAmhr2FstInhaInhbaInhbb
Skeletal Development
BglapBmp1Bmp2Bmp3Bmp4Bmp5Bmp6Bmp7Bmpr2ChrdCol1a1Col1a2Igf1InhaInhbaNog